Both directions of Highway 49 south of Grass Valley are closed due to a collision involving two RVs and a third vehicle, according to Caltrans.
The three-car incident occurred at 1:30 p.m. on Highway 49 at Golden Chain Drive by the Golden Chain Motel.
Three people were injured and one was taken to the hospital but their condition is unknown at this time.
There is no estimated time when both the southbound and northbound lanes will re-open.
Stay with ABC10 as more information is released.