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49ers build 28-point lead, hold on for 41-33 win over Lions

Dre Greenlaw returned an interception for a touchdown and the San Francisco 49ers hang on for a 41-33 win over the Detroit Lions
Credit: AP
San Francisco 49ers wide receiver Trent Sherfield celebrates scoring on a five yard touchdown reception against the Detroit Lions in the first half of an NFL football game in Detroit, Sunday, Sept. 12, 2021. (AP Photo/Duane Burleson)

DETROIT (AP) - Dre Greenlaw returned an interception for a touchdown to help the San Francisco 49ers score 17 points over two-plus minutes late in the first half and they held on for a 41-33 win over the Detroit Lions.

San Francisco led 38-10 early in the fourth quarter and allowed Detroit to score 23 points in three-plus minutes to pull within eight points. The Lions turned over the ball on downs at the San Francisco 24 with 12 seconds left after getting another chance when Deebo Samuel fumbled.