CHICAGO (AP) - Jimmy Garoppolo threw for 322 yards and ran for two touchdowns, and the San Francisco 49ers beat the short-handed Chicago Bears 33-22 to snap a four-game losing streak.
Garoppolo led three touchdown drives in the second half and another possession that ended with a field goal. He scored from the 2 in the third quarter and ran it in from the 5 in the fourth to make it 30-22.
Deebo Samuel had six catches for 171 yards. Elijah Mitchell carried 18 times for 137 yards and a touchdown, helping San Francisco win for the first time since beating both Detroit and Philadelphia on the road to start the season.
Chicago lost its third straight.