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Garoppolo shines in return to NE; Niners crush Patriots 33-6

49ers Quarterback Jimmy Garoppolo finished 20 of 25 for 277 yards with two interceptions in his first game against his former Patriots team.
Credit: AP
New England Patriots quarterback Cam Newton, left, and San Francisco 49ers quarterback Jimmy Garoppolo speak at midfield after an NFL football game, Sunday, Oct. 25, 2020, in Foxborough, Mass. (AP Photo/Charles Krupa)

FOXBOROUGH, Mass. (AP) - Jeff Wilson Jr. rushed for a career-high three touchdowns and 112 yards before leaving the game with an ankle injury and the San Francisco 49ers dominated the New England Patriots in a 33-6 win. 

Jimmy Garoppolo finished 20 of 25 for 277 yards with two interceptions in his first game against his former team.

San Francisco has followed back-to-back losses with two wins. 

Brandon Aiyuk had six catches for 115 yards. 

New England fell to 2-4 for the first time since coach Bill Belichick’s first season in 2000.