Nick Mullens will start at quarterback on Sunday for the San Francisco 49ers in place of the injured Jimmy Garoppolo but won’t have All-Pro tight end George Kittle as an option.
Garoppolo didn’t practice all week because of a high ankle sprain and has been officially ruled out for this week’s game against the New York Giants.
Coach Kyle Shanahan also says Kittle will miss a second straight game after spraining his knee in the season opener.
Kittle practiced on a limited basis but wasn’t healthy enough to go.
