SAN DIEGO (AP) - Joey Lucchesi struck out nine in six innings, fellow rookie Christian Villanueva homered, doubled and drove in three runs, and the San Diego Padres cruised past San Francisco 10-1 on Sunday to beat the Giants for the third straight game.
Jose Pirela was a home run short of the cycle and had three RBIs for the Padres, who have won five of seven. The Giants have lost four of five.
Lucchesi (2-0) was sharp in outpitching Tyler Beede (0-1) in a matchup of 24-year-old rookies. Lucchesi walked none and his nine strikeouts were his most in four big league starts. The lefty allowed one run and five hits.
Lucchesi became the first pitcher from the 2016 draft class to reach the majors after Dinelson Lamet hurt his right elbow in his final spring training start for the Padres. Lucchesi got a no-decision in his big league debut March 30 against Milwaukee and again in a home start versus the Rockies on April 5 before earning his first win at Colorado on Tuesday.
Lamet will have reconstructive elbow surgery this week.
Beede lasted only 3 2/3 innings, permitting five runs and six hits while striking out six and walking three.
Villanueva hit a two-run double in the third and homered off Josh Osich leading off the fifth, his fifth. Villanueva also homered in a 5-4 victory Saturday night.
The Padres chased Beede in their three-run fourth. Cory Spangenberg and Pirela hit RBI doubles, and Freddy Galvis had an RBI single.
Giants: C Buster Posey has a sore thumb but should be OK to play Tuesday night after an off day Monday. ... RHP Jeff Samardzija, on the disabled list with a strained right pectoral muscle, likely will make another rehab start. He threw 62 pitches in 2 2/3 innings Saturday night for Class A San Jose, allowing six runs and five hits with five strikeouts and two walks.
Padres: 1B Eric Hosmer sat out with mild back tightness.
Giants: RHP Johnny Cueto (1-0, 0.69 ERA) is expected to come off the disabled list to start Tuesday night at Arizona. LHP Patrick Corbin (2-0, 2.45) is scheduled to start for the Diamondbacks.
Padres: LHP Robbie Erlin (0-1, 2.38) is the likely starter in place of suspended Luis Perdomo when the Padres open a three-game home series Monday night against the Dodgers. Perdomo was suspended five games for throwing behind Colorado slugger Nolan Arenado on Wednesday. Los Angeles counters with LHP Hyun-Jin Ryu (1-0, 2.79).